STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH85681.1NAD-dependent malic enzyme; Function of strongly homologous gene; enzyme. (490 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 
 0.964
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
  
 0.961
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
  
 
 0.953
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.952
pdhB
Pyruvate dehydrogenase E1 component subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.935
aceE
Fragment of conserved protein of unknown function (part 1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.925
CCH88502.1
Pyruvate carboxylase (fragment); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.925
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.925
pyc-2
Pyruvate carboxylase (fragment); Function of strongly homologous gene; enzyme.
   
 0.925
poxB
Pyruvate dehydrogenase/oxidase: FAD-and thiamine PPi-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family.
  
 
 0.924
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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