STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larCConserved protein of unknown function; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (401 aa)    
Predicted Functional Partners:
CCH89754.1
Homologs of previously reported genes of unknown function.
 
 0.992
purE
1-(5-Phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; Function of strongly homologous gene; enzyme.
 
  
 0.913
CCH89436.1
Homologs of previously reported genes of unknown function.
 
  
 0.839
CCH85739.1
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
 
  
 0.834
CCH87631.1
Homologs of previously reported genes of unknown function.
 
  
 0.821
CCH88476.1
Homologs of previously reported genes of unknown function.
 
  
 0.814
pyrG
CTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
      0.622
CCH88927.1
Homologs of previously reported genes of unknown function.
 
     0.573
CCH85738.1
SAM-dependent methyltransferase; Function of strongly homologous gene; enzyme.
       0.560
CCH85736.1
Homologs of previously reported genes of unknown function.
       0.519
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.