STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH85739.1Diguanylate cyclase; Function of strongly homologous gene; enzyme. (961 aa)    
Predicted Functional Partners:
CCH89754.1
Homologs of previously reported genes of unknown function.
 
  
 0.917
larC
Conserved protein of unknown function; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.855
CCH85740.1
Diguanylate cyclase (GGDEF) domain-containing protein; Function of strongly homologous gene; enzyme.
 
    
0.832
CCH87356.1
Putative Diguanylate cyclase/phosphodiesterase with GAF sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
 
 0.760
CCH89865.1
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
 
 0.754
CCH85860.1
Putative Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
 0.714
CCH89436.1
Homologs of previously reported genes of unknown function.
 
  
 0.699
CCH85629.1
Putative Diguanylate cyclase/phosphodiesterase with GAF sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
 
  0.696
CCH87436.1
Diguanylate phosphodiesterase; Function of strongly homologous gene; enzyme.
 
 0.690
CCH89894.1
Homologs of previously reported genes of unknown function.
 
    0.690
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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