STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
4CLLong-chain-fatty-acid--CoA ligase; Function of strongly homologous gene; enzyme. (532 aa)    
Predicted Functional Partners:
CCH87256.1
AMP-dependent synthetase and ligase (fragment); Function of strongly homologous gene; enzyme.
 
0.920
CCH85767.1
Putative lipase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   0.809
CCH85874.1
Acetoacetyl-CoA synthase; Function of strongly homologous gene; enzyme.
 
 
 0.557
CCH85769.1
Putative phenylacetic acid degradation-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.525
CCH89317.1
3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; Function of strongly homologous gene; enzyme.
  
 
 0.522
CCH88131.1
Butyrate--CoA ligase; Function of strongly homologous gene; enzyme.
 
 
0.475
rplF
50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
    
  0.469
accC
Carbamoyl-phosphate synthase L chain ATP-binding protein; Function of strongly homologous gene; enzyme.
 
 
 0.453
acsA
Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
0.450
CCH86453.1
Homologs of previously reported genes of unknown function.
  
     0.407
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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