STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabG-23-oxoacyl-[acyl-carrier-protein] reductase; Function of strongly homologous gene; enzyme. (446 aa)    
Predicted Functional Partners:
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II (Beta-ketoacyl-ACP synthase II) (KAS II); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.976
CCH85787.1
Putative Acyl dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  0.955
fadI
3-ketoacyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.912
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.892
CCH85784.1
Transcriptional regulator, TetR family; Function of strongly homologous gene; regulator.
 
     0.813
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Function of strongly homologous gene; enzyme.
 
  
 0.733
CCH85783.1
Acyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
 
  0.694
CCH87888.1
Beta-ketoacyl-acyl-carrier-protein synthase III; Function of strongly homologous gene; enzyme.
  
 
 0.687
CCH87000.1
Short-chain dehydrogenase/reductase SDR; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
   0.639
trxA
Thioredoxin; Function of strongly homologous gene; carrier; Belongs to the thioredoxin family.
   
 
 0.636
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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