| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCH85799.1 | CCH85800.1 | MODMU_0338 | MODMU_0339 | Protein of unknown function; No homology to any previously reported sequences. | Homologs of previously reported genes of unknown function. | 0.540 |
| CCH85800.1 | CCH85799.1 | MODMU_0339 | MODMU_0338 | Homologs of previously reported genes of unknown function. | Protein of unknown function; No homology to any previously reported sequences. | 0.540 |
| CCH85800.1 | CCH88979.1 | MODMU_0339 | MODMU_3567 | Homologs of previously reported genes of unknown function. | Putative ATP/GTP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.568 |
| CCH85800.1 | acuC | MODMU_0339 | MODMU_3953 | Homologs of previously reported genes of unknown function. | Acetoin dehydrogenase; Function of strongly homologous gene; enzyme. | 0.626 |
| CCH85800.1 | allC | MODMU_0339 | MODMU_0205 | Homologs of previously reported genes of unknown function. | Allantoicase; Function of strongly homologous gene; enzyme; Belongs to the allantoicase family. | 0.472 |
| CCH85800.1 | arc | MODMU_0339 | MODMU_2598 | Homologs of previously reported genes of unknown function. | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.429 |
| CCH85800.1 | dnaN | MODMU_0339 | MODMU_0003 | Homologs of previously reported genes of unknown function. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.561 |
| CCH85800.1 | glpK | MODMU_0339 | MODMU_5537 | Homologs of previously reported genes of unknown function. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.460 |
| CCH85800.1 | glpK-2 | MODMU_0339 | MODMU_5539 | Homologs of previously reported genes of unknown function. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.460 |
| CCH85800.1 | prcA | MODMU_0339 | MODMU_2604 | Homologs of previously reported genes of unknown function. | 20S proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.484 |
| CCH85800.1 | prcB | MODMU_0339 | MODMU_2603 | Homologs of previously reported genes of unknown function. | Proteasome endopeptidase complex, beta component; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.484 |
| CCH88979.1 | CCH85800.1 | MODMU_3567 | MODMU_0339 | Putative ATP/GTP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Homologs of previously reported genes of unknown function. | 0.568 |
| acuC | CCH85800.1 | MODMU_3953 | MODMU_0339 | Acetoin dehydrogenase; Function of strongly homologous gene; enzyme. | Homologs of previously reported genes of unknown function. | 0.626 |
| acuC | arc | MODMU_3953 | MODMU_2598 | Acetoin dehydrogenase; Function of strongly homologous gene; enzyme. | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.427 |
| allC | CCH85800.1 | MODMU_0205 | MODMU_0339 | Allantoicase; Function of strongly homologous gene; enzyme; Belongs to the allantoicase family. | Homologs of previously reported genes of unknown function. | 0.472 |
| arc | CCH85800.1 | MODMU_2598 | MODMU_0339 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Homologs of previously reported genes of unknown function. | 0.429 |
| arc | acuC | MODMU_2598 | MODMU_3953 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Acetoin dehydrogenase; Function of strongly homologous gene; enzyme. | 0.427 |
| arc | glpK | MODMU_2598 | MODMU_5537 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.944 |
| arc | glpK-2 | MODMU_2598 | MODMU_5539 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.944 |
| arc | prcA | MODMU_2598 | MODMU_2604 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 20S proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.998 |