STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH85850.1HAD-superfamily hydrolase, subfamily IA; Function of strongly homologous gene; enzyme. (221 aa)    
Predicted Functional Partners:
mtlA
PTS system mannitol-specific EIICBA component [Includes: Mannitol permease IIC component; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
  0.748
rbn
Ribonuclease BN; Function of strongly homologous gene; enzyme.
 
    0.732
CCH88957.1
Homologs of previously reported genes of unknown function.
 
    0.730
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.709
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
   
 
  0.701
CCH85747.1
IMP dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.687
adhB
Alcohol dehydrogenase B, Zn-dependent; Function of strongly homologous gene; enzyme.
       0.565
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.565
CCH87716.1
FAD/FMN-dependent dehydrogenase; Function of strongly homologous gene; enzyme.
    
 0.535
CCH90542.1
D-lactate dehydrogenase (cytochrome); Function of strongly homologous gene; enzyme.
    
 0.535
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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