STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lldDLactate 2-monooxygenase; Function of strongly homologous gene; enzyme. (432 aa)    
Predicted Functional Partners:
poxB
Pyruvate dehydrogenase/oxidase: FAD-and thiamine PPi-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family.
  
 
 0.929
lldD-3
L-lactate dehydrogenase; Function of strongly homologous gene; enzyme.
  
  
 
0.923
lldD-2
L-lactate dehydrogenase [cytochrome] 2; Function of strongly homologous gene; enzyme.
  
  
 
0.918
acsA
Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.908
CCH88131.1
Butyrate--CoA ligase; Function of strongly homologous gene; enzyme.
   
 
 0.908
CCH88351.1
Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
 
 
 
 0.908
ald-2
Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
 
 
 
 0.908
CCH89436.1
Homologs of previously reported genes of unknown function.
    
  0.900
CCH89820.1
Acylphosphatase; Function of strongly homologous gene; enzyme.
     
  0.900
lutP
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.676
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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