STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH86060.1NUDIX hydrolase; Function of strongly homologous gene; enzyme. (255 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
    
 0.935
CCH86059.1
Thiol-disulfide isomerase-like thioredoxin; Function of strongly homologous gene; carrier.
  
  0.926
CCH86062.1
Trypsin-like serine protease with C-terminal PDZ domain; Function of strongly homologous gene; enzyme.
  
 
  0.857
nnrE
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
 0.850
CCH86061.1
Protein of unknown function; No homology to any previously reported sequences.
       0.773
CCH87034.1
Thioredoxin; Function of strongly homologous gene; enzyme.
  
  0.687
CCH87086.1
Putative Redoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
  0.687
CCH87044.1
Thioredoxin of cytochrome c-type biogenesis; Function of strongly homologous gene; cell process.
  
  0.601
CCH87270.1
Ribonuclease II; Function of strongly homologous gene; enzyme.
   
 0.575
CCH86056.1
Transcriptional regulator, Crp/Fnr family; Function of strongly homologous gene; regulator.
       0.503
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.