STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobBCobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (460 aa)    
Predicted Functional Partners:
cobH
Precorrin-8X methylmutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
CCH86076.1
Putative Threonine-phosphate decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.998
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
  
 0.997
cobO
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.992
cobN
Aerobic cobaltochelatase subunit cobN; Function of strongly homologous gene; enzyme.
 
 
 0.992
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.990
cysG
Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme.
  
 0.980
cobIJ
Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme.
 
  
 0.974
cobU
Adenosylcobinamide-phosphateguanylyltransferase; Function of strongly homologous gene; enzyme.
 
 
 0.960
cobL
Precorrin-6Y C(5,15)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.958
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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