Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
chlDCobaltochelatase subunit; Function of strongly homologous gene; transporter. (687 aa)    
Predicted Functional Partners:
cobN
Aerobic cobaltochelatase subunit cobN; Function of strongly homologous gene; enzyme.
 
 0.986
cobO
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.957
CCH86437.1
Mg-chelatase; Function of strongly homologous gene; enzyme.
  
 0.951
hemY
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.950
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.942
cobB
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.922
cobIJ
Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme.
 
   
 0.887
cysG
Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme.
  
  
 0.856
cobL
Precorrin-6Y C(5,15)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.828
CCH88965.1
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.792
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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