cobQ protein (Modestobacter marinus) - STRING interaction network

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cobQ

Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (499 aa)

Predicted Functional Partners:

cobIJ

0.999

cobD

0.997

cobO

0.995

cobH

0.995

cobB

0.990

cobU

0.985

cobM

0.978

cobK

0.964

cobL

0.954

cobS

0.952

Your Current Organism:

Modestobacter marinus

NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cobB	cobD	MODMU_0624	MODMU_0642	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	0.922
cobB	cobH	MODMU_0624	MODMU_0656	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Precorrin-8X methylmutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.999
cobB	cobIJ	MODMU_0624	MODMU_0655	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme.	0.974
cobB	cobK	MODMU_0624	MODMU_0647	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Precorrin-6A reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.815
cobB	cobL	MODMU_0624	MODMU_0644	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Precorrin-6Y C(5,15)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.958
cobB	cobM	MODMU_0624	MODMU_0645	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Precorrin-4 C(11)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.	0.919
cobB	cobO	MODMU_0624	MODMU_0625	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.992
cobB	cobQ	MODMU_0624	MODMU_0638	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.	0.990
cobB	cobS	MODMU_0624	MODMU_0669	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.	0.841
cobB	cobU	MODMU_0624	MODMU_0670	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	Adenosylcobinamide-phosphateguanylyltransferase; Function of strongly homologous gene; enzyme.	0.960
cobD	cobB	MODMU_0642	MODMU_0624	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	0.922
cobD	cobH	MODMU_0642	MODMU_0656	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Precorrin-8X methylmutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.927
cobD	cobIJ	MODMU_0642	MODMU_0655	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme.	0.965
cobD	cobK	MODMU_0642	MODMU_0647	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Precorrin-6A reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.768
cobD	cobL	MODMU_0642	MODMU_0644	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Precorrin-6Y C(5,15)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.969
cobD	cobM	MODMU_0642	MODMU_0645	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Precorrin-4 C(11)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.	0.963
cobD	cobO	MODMU_0642	MODMU_0625	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.987
cobD	cobQ	MODMU_0642	MODMU_0638	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.	0.997
cobD	cobS	MODMU_0642	MODMU_0669	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.	0.894
cobD	cobU	MODMU_0642	MODMU_0670	Cobalamin biosynthetic protein (anaerobic pathway of cobalamin biosynthesis, cobD); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	Adenosylcobinamide-phosphateguanylyltransferase; Function of strongly homologous gene; enzyme.	0.972

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