| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCH86137.1 | hppA | MODMU_0680 | MODMU_0681 | DEAD/DEAH box helicase; Function of strongly homologous gene; enzyme. | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.638 |
| CCH86137.1 | topA | MODMU_0680 | MODMU_0684 | DEAD/DEAH box helicase; Function of strongly homologous gene; enzyme. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.552 |
| CCH86139.1 | CCH86140.1 | MODMU_0682 | MODMU_0683 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.773 |
| CCH86139.1 | hppA | MODMU_0682 | MODMU_0681 | Homologs of previously reported genes of unknown function. | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.478 |
| CCH86139.1 | topA | MODMU_0682 | MODMU_0684 | Homologs of previously reported genes of unknown function. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.440 |
| CCH86140.1 | CCH86139.1 | MODMU_0683 | MODMU_0682 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.773 |
| CCH86140.1 | hppA | MODMU_0683 | MODMU_0681 | Homologs of previously reported genes of unknown function. | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.478 |
| CCH86140.1 | ribD-2 | MODMU_0683 | MODMU_3300 | Homologs of previously reported genes of unknown function. | Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.528 |
| CCH86140.1 | topA | MODMU_0683 | MODMU_0684 | Homologs of previously reported genes of unknown function. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.440 |
| cspA | hppA | MODMU_0781 | MODMU_0681 | Cold shock protein, DNA binding; Function of homologous gene experimentally demonstrated in an other organism; factor. | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.546 |
| cspA-2 | hppA | MODMU_3901 | MODMU_0681 | Cold shock protein, DNA binding; Function of homologous gene experimentally demonstrated in an other organism; factor. | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.546 |
| cspC | hppA | MODMU_0835 | MODMU_0681 | Cold shock-like protein CspC; Function of strongly homologous gene; factor. | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.546 |
| hppA | CCH86137.1 | MODMU_0681 | MODMU_0680 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | DEAD/DEAH box helicase; Function of strongly homologous gene; enzyme. | 0.638 |
| hppA | CCH86139.1 | MODMU_0681 | MODMU_0682 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | Homologs of previously reported genes of unknown function. | 0.478 |
| hppA | CCH86140.1 | MODMU_0681 | MODMU_0683 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | Homologs of previously reported genes of unknown function. | 0.478 |
| hppA | cspA | MODMU_0681 | MODMU_0781 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | Cold shock protein, DNA binding; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.546 |
| hppA | cspA-2 | MODMU_0681 | MODMU_3901 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | Cold shock protein, DNA binding; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.546 |
| hppA | cspC | MODMU_0681 | MODMU_0835 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | Cold shock-like protein CspC; Function of strongly homologous gene; factor. | 0.546 |
| hppA | nnrE | MODMU_0681 | MODMU_4872 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.402 |
| hppA | ribBA | MODMU_0681 | MODMU_3298 | Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.593 |
