STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH86140.1Homologs of previously reported genes of unknown function. (513 aa)    
Predicted Functional Partners:
CCH86139.1
Homologs of previously reported genes of unknown function.
       0.773
CCH85589.1
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
     0.516
CCH89683.1
Phosphoesterase PA-phosphatase; Function of strongly homologous gene; enzyme.
  
    0.513
CCH86872.1
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
     0.481
hppA
Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
       0.478
CCH86230.1
ABC-type multidrug transport system, ATPase component; Function of strongly homologous gene; transporter.
 
    0.466
ribD-2
Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.441
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.440
CCH90223.1
Monofunctional chorismate mutase; Function of strongly homologous gene; enzyme.
  
     0.427
CCH86142.1
SAM-dependent methyltransferase; Function of strongly homologous gene; enzyme.
       0.425
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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