STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nadCQuinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family. (311 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase (Quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.999
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
   
 0.983
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.976
CCH85541.1
Competence/damage-inducible CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
    
 0.918
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
   
 0.906
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
    
  0.900
CCH89880.1
Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family.
    
  0.899
nagD
N-Acetylglucosamine-6-Phosphatase, Protein nagD; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the HAD-like hydrolase superfamily.
   
 
  0.899
nudC
NADH pyrophosphatase; Function of strongly homologous gene; enzyme; Belongs to the Nudix hydrolase family.
     
 0.899
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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