STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
disADNA integrity scanning protein disA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. (360 aa)    
Predicted Functional Partners:
radA
DNA repair protein radA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.961
CCH87197.1
Homologs of previously reported genes of unknown function.
  
     0.735
CCH89757.1
Phosphoesterase; Function of strongly homologous gene; enzyme.
  
   
 0.700
CCH90198.1
2'-5' RNA ligase; Function of strongly homologous gene; enzyme.
  
     0.534
CCH88103.1
Homologs of previously reported genes of unknown function.
  
     0.525
CCH88102.1
Homologs of previously reported genes of unknown function.
  
     0.494
CCH85493.1
Homologs of previously reported genes of unknown function.
  
     0.484
CCH86208.1
Homologs of previously reported genes of unknown function.
     
 0.483
CCH88098.1
Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator.
  
     0.472
CCH88101.1
Homologs of previously reported genes of unknown function.
  
     0.467
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.