STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH86230.1ABC-type multidrug transport system, ATPase component; Function of strongly homologous gene; transporter. (959 aa)    
Predicted Functional Partners:
CCH86231.1
Putative ABC transporter (permease); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 0.966
CCH88904.1
ABC transporter membrane protein; Function of strongly homologous gene; transporter.
 
 0.721
CCH90015.1
Homologs of previously reported genes of unknown function.
  
 
  0.633
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
    
 0.621
CCH86229.1
Protein of unknown function; No homology to any previously reported sequences.
       0.620
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.612
CCH86228.1
Homologs of previously reported genes of unknown function.
       0.562
CCH88856.1
Homologs of previously reported genes of unknown function.
  
     0.562
CCH86225.1
Homologs of previously reported genes of unknown function.
 
     0.544
CCH89955.1
Peptidase S26A, superoxide dismutase maturation protease, nickel-type; Function of strongly homologous gene; enzyme.
  
    0.543
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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