STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
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[Homology]
Score
cobB-2Sir2-family regulator protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (281 aa)    
Predicted Functional Partners:
CCH86363.1
Homologs of previously reported genes of unknown function.
     
 0.781
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
  
 
 0.769
CCH86364.1
Homologs of previously reported genes of unknown function.
       0.727
CCH89774.1
Cell envelope-related function transcriptional attenuator common domain; Function of strongly homologous gene; regulator.
   
    0.723
CCH86023.1
Transcriptional regulator, HxlR family; Function of strongly homologous gene; regulator.
  
    0.715
nudC
NADH pyrophosphatase; Function of strongly homologous gene; enzyme; Belongs to the Nudix hydrolase family.
  
  0.703
nadE-2
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.700
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.699
CCH90635.1
MarR family transcriptional regulator.
   
    0.676
pncA
Nicotinamidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.649
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.