STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH86430.1Putative uracil-DNA glycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (259 aa)    
Predicted Functional Partners:
CCH90250.1
Uracil-DNA glycosylase; Function of strongly homologous gene; enzyme.
  
  
  0.924
CCH86333.1
Uracil-DNA glycosylase; Function of strongly homologous gene; enzyme.
  
  
  0.913
CCH90636.1
Putative extracellular metal binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
      0.666
uvrC
Excinuclease, UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
    
 0.589
CCH86429.1
Homologs of previously reported genes of unknown function.
       0.562
CCH86431.1
Homologs of previously reported genes of unknown function.
       0.500
mutM-2
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.451
CCH90244.1
Putative glycoprotease M22; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.435
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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