STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tag3-methyl-adenine DNA glycosylase I, constitutive; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (171 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
      0.895
CCH86612.1
Homologs of previously reported genes of unknown function.
     
 0.836
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.639
ada
Transcriptional regulator, Ada family; Function of strongly homologous gene; factor.
     
 0.606
mutY
A/G-specific DNA-adenine glycosylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.558
CCH86610.1
Putative epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
       0.557
CCH90400.1
Short-chain dehydrogenase/reductase SDR; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      0.494
CCH85541.1
Competence/damage-inducible CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
  
    0.476
parA-3
Chromosome segregation ATPase; Function of homologous gene experimentally demonstrated in an other organism; cell process.
      
 0.454
mutM-2
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
      
 0.452
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.