STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH86619.1Phytoene desaturase; Function of strongly homologous gene; enzyme. (500 aa)    
Predicted Functional Partners:
crtB
Phytoene synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.972
CCH88898.1
Homologs of previously reported genes of unknown function.
 
  
 0.839
CCH88899.1
Glycosyl transferase family 2; Function of strongly homologous gene; enzyme.
 
  
  0.804
chlD
Cobaltochelatase subunit; Function of strongly homologous gene; transporter.
 
 
 0.617
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
      
 0.563
crtO
Beta-carotene ketolase; Function of strongly homologous gene; enzyme.
  
     0.523
CCH86620.1
Homologs of previously reported genes of unknown function.
       0.521
CCH88965.1
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.509
CCH85822.1
Geranylgeranyl reductase; Function of strongly homologous gene; enzyme.
 
 
 0.507
CCH86308.1
NAD/FAD-dependent oxidoreductase; Function of strongly homologous gene; enzyme.
  
   
 0.403
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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