Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH86704.1Thioredoxin-disulfide reductase; Function of strongly homologous gene; enzyme. (546 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.840
CCH89435.1
Two-component sensor histidine kinase; Function of strongly homologous gene; enzyme.
 
 
 0.818
CCH87488.1
Two component signal transduction histidine kinase; Function of strongly homologous gene; enzyme.
 
  
 0.814
CCH87733.1
Sensor kinase, two-component system; Function of strongly homologous gene; enzyme.
  
  
 0.784
CCH90729.1
Homologs of previously reported genes of unknown function.
 
     0.736
gcvP
Glycine cleavage system P-protein (glycine dehydrogenase); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.709
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Function of strongly homologous gene; enzyme.
   
   0.687
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
     
 0.662
CCH89838.1
Putative cystathionine gamma-lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.661
sufS
Cysteine desulfurase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 
  0.655
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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