Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH86741.1Glyoxalase/bleomycin resistance protein/dioxygenase; Function of strongly homologous gene; cell process. (140 aa)    
Predicted Functional Partners:
CCH86740.1
Transcriptional regulator RamA, AraC family; Function of strongly homologous gene; regulator.
 
     0.937
CCH86375.1
Transcriptional regulator, AraC family; Function of strongly homologous gene; regulator.
 
     0.711
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
   
 
 0.603
icmF
Methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.580
kdpE
Two-component system, OmpR family, KDP operon response regulator KdpE; Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
 0.531
kdpD
Sensor protein kdpD; Function of strongly homologous gene; enzyme.
  
    0.531
mutB
Methylmalonyl-CoA mutase large subunit (MCM-alpha); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.493
CCH87887.1
acetyl-CoA carboxylase, biotin carboxylase subunit; Function of strongly homologous gene; enzyme.
  
 
 0.492
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
  0.461
CCH86438.1
L-threonine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
  0.452
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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