close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH86769.1Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the AB hydrolase superfamily. MetX family. (337 aa)    
Predicted Functional Partners:
CCH86142.1
SAM-dependent methyltransferase; Function of strongly homologous gene; enzyme.
  
  
 0.807
CCH86771.1
Oxidoreductase molybdopterin binding; Function of strongly homologous gene; enzyme.
       0.773
fdnI
Formate dehydrogenase gamma subunit; Function of strongly homologous gene; enzyme.
       0.768
metC
O-acetylhomoserine/O-acetylserine sulfhydrylase; Function of strongly homologous gene; enzyme.
 
  
 0.751
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.747
metC-2
O-acetylhomoserine/O-acetylserine sulfhydrylase; Function of strongly homologous gene; enzyme.
 
  
 0.742
CCH86768.1
Intracellular protease, PfpI family; Function of strongly homologous gene; enzyme.
       0.584
metK
Methionine adenosyltransferase 1 (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
   
 0.412
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.