STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (431 aa)    
Predicted Functional Partners:
pncA
Nicotinamidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
nadC
Quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.
   
 0.983
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.978
CCH85541.1
Competence/damage-inducible CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
  
 
 0.954
nudC
NADH pyrophosphatase; Function of strongly homologous gene; enzyme; Belongs to the Nudix hydrolase family.
    
 0.913
punA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.912
CCH89880.1
Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family.
  
 
 0.910
nagD
N-Acetylglucosamine-6-Phosphatase, Protein nagD; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the HAD-like hydrolase superfamily.
   
 
  0.899
CCH89725.1
Competence/damage-inducible protein cinA; Function of strongly homologous gene; cell process; Belongs to the CinA family.
  
 
 0.804
nadE-2
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.799
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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