| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCH86839.1 | arc | MODMU_1390 | MODMU_2598 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.939 |
| CCH86839.1 | cysM | MODMU_1390 | MODMU_1392 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cysteine synthase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.866 |
| CCH86839.1 | glpK | MODMU_1390 | MODMU_5537 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.866 |
| CCH86839.1 | glpK-2 | MODMU_1390 | MODMU_5539 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.866 |
| CCH86839.1 | moaD | MODMU_1390 | MODMU_1391 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Molybdopterin synthase subunit MoaD; Function of strongly homologous gene; enzyme. | 0.966 |
| CCH86839.1 | moeB | MODMU_1390 | MODMU_4648 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Molybdopterin-synthase sulfurylase; Function of strongly homologous gene; enzyme. | 0.877 |
| CCH86839.1 | prcA | MODMU_1390 | MODMU_2604 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 20S proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.853 |
| CCH86839.1 | prcB | MODMU_1390 | MODMU_2603 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Proteasome endopeptidase complex, beta component; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.853 |
| CCH86839.1 | rpsC | MODMU_1390 | MODMU_4913 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.873 |
| CCH86839.1 | rpsS | MODMU_1390 | MODMU_4915 | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.849 |
| arc | CCH86839.1 | MODMU_2598 | MODMU_1390 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.939 |
| arc | glpK | MODMU_2598 | MODMU_5537 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.879 |
| arc | glpK-2 | MODMU_2598 | MODMU_5539 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.879 |
| arc | prcA | MODMU_2598 | MODMU_2604 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 20S proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.991 |
| arc | prcB | MODMU_2598 | MODMU_2603 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Proteasome endopeptidase complex, beta component; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.985 |
| arc | rpsC | MODMU_2598 | MODMU_4913 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.404 |
| cysM | CCH86839.1 | MODMU_1392 | MODMU_1390 | Cysteine synthase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.866 |
| cysM | moaD | MODMU_1392 | MODMU_1391 | Cysteine synthase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Molybdopterin synthase subunit MoaD; Function of strongly homologous gene; enzyme. | 0.973 |
| cysM | moeB | MODMU_1392 | MODMU_4648 | Cysteine synthase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Molybdopterin-synthase sulfurylase; Function of strongly homologous gene; enzyme. | 0.715 |
| glpK | CCH86839.1 | MODMU_5537 | MODMU_1390 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Putative metal-dependent protease of the PAD1/JAB1 superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.866 |
