STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH86873.1Methylenetetrahydrofolate reductase; Function of strongly homologous gene; enzyme. (348 aa)    
Predicted Functional Partners:
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.982
CCH86874.1
Methyltransferase type 11, S-adenosyl-L-methionine-dependent; Function of strongly homologous gene; enzyme.
 
     0.927
gcvP
Glycine cleavage system P-protein (glycine dehydrogenase); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.732
CCH86933.1
FAD/FMN-dependent dehydrogenase; Function of strongly homologous gene; enzyme.
 
     0.662
CCH86268.1
Homologs of previously reported genes of unknown function.
  
     0.622
CCH86948.1
Putative creatinine amidohydrolase (Creatininase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.614
CCH86940.1
Homologs of previously reported genes of unknown function.
 
     0.609
CCH89838.1
Putative cystathionine gamma-lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.607
metB
Cystathionine gamma-synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.607
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Function of strongly homologous gene; enzyme.
  
 
 0.600
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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