Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH86955.1Peptidase S1; Function of strongly homologous gene; enzyme. (375 aa)    
Predicted Functional Partners:
arc
Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.700
CCH86953.1
Putative FAD linked oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  0.651
CCH90658.1
Sensor protein with an histidine kinase signal transduction domain; Function of strongly homologous gene; regulator.
  
  
 0.604
CCH86954.1
Putative Glyoxalase/bleomycin resistance protein/dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.568
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.512
glpK-2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.512
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
 
 
 
 0.498
mtrA
Two component DNA-binding response regulator mtrA; Function of strongly homologous gene; regulator.
 
  
 0.482
phoB-2
Two-component Pi uptake response regulator, system with PhoR (OmpR family); Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
  
 0.478
CCH85641.1
Homologs of previously reported genes of unknown function.
   
 0.452
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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