Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (416 aa)    
Predicted Functional Partners:
kynA
Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.991
CCH85525.1
Putative secreted metal-dependent cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.825
CCH87752.1
Putative cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.825
CCH87828.1
Putative cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.825
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
  0.696
katA-2
Catalase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the catalase family.
   
 
  0.696
CCH87930.1
Protein of unknown function; No homology to any previously reported sequences.
    
  0.663
amiB
Amidase amiB2; Function of strongly homologous gene; enzyme; Belongs to the amidase family.
       0.564
hmgA
Homogentisate 1,2-dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.521
CCH86996.1
Homologs of previously reported genes of unknown function.
       0.512
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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