STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpiBRibose-5-phosphate isomerase B; Function of strongly homologous gene; enzyme. (161 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase; Function of strongly homologous gene; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.
 
 
 0.949
tkt
Transketolase; Function of strongly homologous gene; enzyme; Belongs to the transketolase family.
  
 
 0.942
CCH88337.1
Transketolase N-terminal section (TK); Function of strongly homologous gene; enzyme.
 
 
 0.935
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.933
CCH88336.1
Transketolase C-terminal section; Function of strongly homologous gene; enzyme.
 
 
 0.933
tal
Transaldolase subfamily; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
 
  
 0.928
gnd
6-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
    
 0.925
gndA
6-phosphogluconate dehydrogenase (Decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.918
upp
Uracil phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UPRTase family.
 
  
 0.916
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.912
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (28%) [HD]