STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH87025.1Bifunctional deaminase-reductase domain protein (fragment); Function of strongly homologous gene; enzyme. (64 aa)    
Predicted Functional Partners:
CCH87714.1
Dihydrofolate reductase; Function of strongly homologous gene; enzyme.
  
     0.747
CCH87243.1
Dihydrofolate reductase; Function of strongly homologous gene; enzyme.
  
     0.743
CCH87026.1
Protein of unknown function; No homology to any previously reported sequences.
       0.651
CCH85814.1
Putative Riboflavin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.598
CCH87797.1
Homologs of previously reported genes of unknown function.
  
     0.555
CCH89245.1
Membrane protein of unknown function; No homology to any previously reported sequences.
  
    0.505
thyA
Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.474
CCH87842.1
Homologs of previously reported genes of unknown function.
  
     0.463
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.