Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
actP-2Copper-transporting P-type ATPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (789 aa)    
Predicted Functional Partners:
CCH87061.1
Copper chaperone (modular protein); Function of strongly homologous gene; structure.
 
 
 0.871
copZ
Copper insertion chaperone and transporter component; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
 
 0.766
CCH87062.1
Homologs of previously reported genes of unknown function.
       0.615
csoR
Copper-sensing transcriptional repressor csoR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
  
 0.584
nuoA
NADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
     
 0.509
CCH87065.1
Putative NADH:ubiquinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.489
nuoH
NADH-quinone oxidoreductase subunit H; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.436
ctpI
Cation-transporting ATPase I; Function of strongly homologous gene; enzyme.
 
 
0.432
CCH88145.1
Cation-transporting ATPase E; Function of strongly homologous gene; enzyme.
 
 
0.424
nuoJ
NADH-quinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
       0.412
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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