STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
coxEProtein containing von Willebrand factor type A (VWA) domain CoxE-like; Function of strongly homologous gene; cell process. (479 aa)    
Predicted Functional Partners:
coxD
Carbon monoxide dehydrogenase, coxD ATPase accessory protein; Function of strongly homologous gene; enzyme.
 
  
 0.958
CCH90792.1
Putative ATPase, AAA family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.794
proA
Gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.766
CCH90791.1
VWA containing CoxE family protein; Function of strongly homologous gene; structure.
  
     0.615
proB
Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.549
obg
Conserved protein of unknown function; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.500
def-2
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.488
CCH87167.1
Putative N-acetyltransferase (GCN5-related); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.488
coxG
Carbon monoxide dehydrogenase subunit G; Function of strongly homologous gene; cell process.
 
     0.457
CCH87711.1
Membrane protein of unknown function; No homology to any previously reported sequences.
  
     0.414
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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