STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pccBPropionyl-CoA carboxylase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (471 aa)    
Predicted Functional Partners:
bccA
Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Biotin carboxylase; Function of strongly homologous gene; enzyme.
 
 0.996
accC
Carbamoyl-phosphate synthase L chain ATP-binding protein; Function of strongly homologous gene; enzyme.
 
 0.990
mce
Methylmalonyl-CoA epimerase; Function of strongly homologous gene; enzyme.
 
 
 0.989
CCH86900.1
Acetyl/propionyl-CoA carboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
 
 0.982
fabD-2
Malonyl CoA-acyl carrier protein transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.966
CCH90147.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 0.961
CCH90146.1
Putative propionyl-CoA carboxylase beta chain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 
0.954
accB
Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.942
CCH89967.1
Pyruvate carboxylase; Function of strongly homologous gene; enzyme.
 
 0.941
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.935
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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