Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aceEFragment of conserved protein of unknown function (part 1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (937 aa)    
Predicted Functional Partners:
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Function of strongly homologous gene; enzyme.
 
 0.991
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of strongly homologous gene; enzyme.
 
 0.966
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
 
 0.961
CCH87101.1
Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.953
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
  
 
 0.953
bfmBC
Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.953
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
     
 0.936
pgi
Glucose-6-phosphate isomerase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
  
 
 0.912
tkt
Transketolase; Function of strongly homologous gene; enzyme; Belongs to the transketolase family.
   
 
 0.902
korB
2-oxoacid:ferredoxin oxidoreductase, beta subunit; Function of strongly homologous gene; enzyme.
     
 0.881
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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