Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (336 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase (Quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.
 0.999
nadC
Quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.
 
 0.999
CCH87695.1
Nicotinamide mononucleotide transporter pnuC; Function of strongly homologous gene; transporter.
  
  
 0.862
CCH88114.1
Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.839
CCH87853.1
Succinate dehydrogenase; Function of strongly homologous gene; enzyme.
  
 0.787
ribD-2
Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.785
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.758
sdhA
Succinate dehydrogenase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.695
CCH87178.1
ComEC/Rec2-related protein (modular protein); Function of strongly homologous gene; cell process.
     
 0.634
iscS
Cysteine desulfurase; Function of strongly homologous gene; enzyme.
  
  
 0.629
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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