STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH87337.1Putative membrane protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (309 aa)    
Predicted Functional Partners:
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.853
ftsH-2
Cell division protease ftsH homolog 4; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.853
CCH85490.1
Rhomboid Peptidase S54; Function of strongly homologous gene; enzyme.
   
 0.613
arc
Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.583
CCH87501.1
Homologs of previously reported genes of unknown function.
 
  
 0.552
CCH90944.1
Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family.
   
    0.549
glnA
Glutamine synthetase 2; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family.
       0.542
CCH88979.1
Putative ATP/GTP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
 0.538
CCH90920.1
Homologs of previously reported genes of unknown function.
     
 0.496
ctpI
Cation-transporting ATPase I; Function of strongly homologous gene; enzyme.
 
 
 0.437
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.