Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH87378.1Zn-dependent protease; Function of strongly homologous gene; enzyme. (313 aa)    
Predicted Functional Partners:
CCH87377.1
Transcriptional regulator, CopY family; Function of strongly homologous gene; factor.
 
 
  0.970
blaI-2
Transcriptional regulator blaI; Function of strongly homologous gene; regulator.
 
 
  0.894
blaI
Transcriptional regulator blaI; Function of strongly homologous gene; regulator.
 
 
  0.873
CCH87379.1
Blue (Type 1) copper domain protein; Function of strongly homologous gene; carrier.
       0.584
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.494
ftsH-2
Cell division protease ftsH homolog 4; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.494
CCH87376.1
Peptidase M23; Function of strongly homologous gene; enzyme.
     
 0.476
CCH90398.1
Homologs of previously reported genes of unknown function.
  
     0.460
CCH87373.1
Cytochrome c oxidase caa3-type, assembly factor CtaG-related protein; Function of strongly homologous gene; enzyme.
 
     0.455
grpE
Molecular chaperone GrpE (Heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
  
  
 0.412
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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