STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnA-3Glutamine synthetase I (Glutamate--ammonia ligase I) (GSI); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (477 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.988
nasD
Rieske (2Fe-2S) iron-sulphur domain protein; Function of strongly homologous gene; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.967
gltD
Glutamate synthase [NADPH] small chain, (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.951
gdh
Glutamate dehydrogenase (NAD); Function of strongly homologous gene; enzyme.
     
 0.948
glnA-4
Glutamine synthetase; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family.
  
  
0.933
carA
Carbamoyl-phosphate synthase small chain; Function of strongly homologous gene; enzyme; Belongs to the CarA family.
 
 
 0.929
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.929
glnA
Glutamine synthetase 2; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family.
 
  
0.925
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
 0.924
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
 
  
 0.917
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.