STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CCH87489.1Putative CyaI3 adenylate/guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (1085 aa)    
Predicted Functional Partners:
CCH89435.1
Two-component sensor histidine kinase; Function of strongly homologous gene; enzyme.
  
 0.810
CCH87488.1
Two component signal transduction histidine kinase; Function of strongly homologous gene; enzyme.
  
 0.658
CCH90165.1
Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.577
CCH90658.1
Sensor protein with an histidine kinase signal transduction domain; Function of strongly homologous gene; regulator.
   
 
 0.571
CCH87876.1
Putative Major facilitator superfamily MFS_1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 0.505
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.449
CCH86056.1
Transcriptional regulator, Crp/Fnr family; Function of strongly homologous gene; regulator.
 
 0.446
nhaA-3
Putative cyclic nucleotide-binding protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
  
 0.413
nthA
Fragment of Nitrile hydratase subunit beta (Nitrilase) (NHase) (part 2); Function of strongly homologous gene; enzyme.
  
     0.411
CCH88147.1
Putative Adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.402
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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