Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fabG-33-oxoacyl-[acyl-carrier-protein] reductase; Function of strongly homologous gene; enzyme. (234 aa)    
Predicted Functional Partners:
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II (Beta-ketoacyl-ACP synthase II) (KAS II); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.892
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Function of strongly homologous gene; enzyme.
 
 
0.886
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.884
fabD-2
Malonyl CoA-acyl carrier protein transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.883
fabD
Acyl-carrier-protein S-malonyltransferase; Function of strongly homologous gene; enzyme.
 
 0.792
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.774
CCH85582.1
Putative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.760
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.706
CCH85610.1
Polyketide beta-ketoacyl synthase 2; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.676
curA
Polyketide beta-ketoacyl synthase 1; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.675
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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