Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH87511.1DNA polymerase LigD, polymerase domain; Function of strongly homologous gene; enzyme. (304 aa)    
Predicted Functional Partners:
CCH87510.1
DNA polymerase LigD, ligase domain protein; Function of strongly homologous gene; enzyme.
  
 0.999
lig
ATP-dependent DNA ligase; Function of strongly homologous gene; enzyme.
  
 0.989
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.980
CCH86845.1
DNA primase, small subunit; Function of strongly homologous gene; enzyme.
 
  
 
0.926
ligB
ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
 0.842
CCH89086.1
Putative DNA polymerase LigD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 
0.806
xthA
Exodeoxyribonuclease III; Function of strongly homologous gene; enzyme.
 
    0.750
fur
Ferric uptake regulation protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the Fur family.
     
 0.525
katA-2
Catalase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the catalase family.
       0.518
CCH87508.1
Homologs of previously reported genes of unknown function.
       0.459
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.