STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdxYPyridoxamine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyridoxine kinase family. (283 aa)    
Predicted Functional Partners:
pdxS
Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
   
 0.922
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.919
CCH86866.1
Putative aldo/keto reductase, NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
  0.900
pdxH
Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
    
 0.863
pdxH-2
Pyridoxine/pyridoxamine 5'-phosphate oxidase; Function of strongly homologous gene; enzyme.
    
 0.863
CCH86823.1
Aldo/keto reductase, NAD(P)-binding; Function of strongly homologous gene; enzyme.
  
 
  0.859
CCH87579.1
Homologs of previously reported genes of unknown function; Belongs to the UPF0303 family.
       0.773
thiD
Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.769
CCH87581.1
Homologs of previously reported genes of unknown function.
       0.668
CCH87582.1
NADPH-dependent fmn reductase.
       0.668
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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