Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH87608.1Fumarylacetoacetate hydrolase family protein; Function of strongly homologous gene; enzyme. (283 aa)    
Predicted Functional Partners:
CCH89599.1
Amidohydrolase; Function of strongly homologous gene; enzyme.
      0.896
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
  
 0.831
CCH87607.1
Homologs of previously reported genes of unknown function.
 
    0.820
CCH87609.1
Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.773
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
  0.771
fahA-2
Fumarylacetoacetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.754
sdhC
Succinate dehydrogenase/fumarate reductase cytochrome b subunit, b558 family; Function of strongly homologous gene; enzyme.
    
  0.748
aceA
Isocitrate lyase; Function of strongly homologous gene; enzyme.
     
  0.741
CCH89421.1
Short-chain dehydrogenase/reductase SDR; Function of strongly homologous gene; enzyme.
   
  0.657
sdhA
Succinate dehydrogenase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
  0.653
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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