Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH87631.1Homologs of previously reported genes of unknown function. (421 aa)    
Predicted Functional Partners:
CCH89754.1
Homologs of previously reported genes of unknown function.
 
  
 0.858
purE
1-(5-Phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; Function of strongly homologous gene; enzyme.
 
  
 0.842
larC
Conserved protein of unknown function; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.814
uxaC
Uronate isomerase; Function of strongly homologous gene; enzyme.
 
     0.739
CCH85739.1
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
 
  
 0.663
CCH87629.1
Fructuronate reductase; Function of strongly homologous gene; enzyme.
 
     0.638
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
     
 0.610
CCH87716.1
FAD/FMN-dependent dehydrogenase; Function of strongly homologous gene; enzyme.
    
  0.496
CCH90542.1
D-lactate dehydrogenase (cytochrome); Function of strongly homologous gene; enzyme.
    
  0.496
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.459
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.