STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fahA-2Fumarylacetoacetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (408 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.969
hpd
4-hydroxyphenylpyruvate dioxygenase (HPPDase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.907
CCH87893.1
Homologs of previously reported genes of unknown function.
 
     0.889
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
  0.784
sdhA
Succinate dehydrogenase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
  0.776
CCH87891.1
Transcriptional regulator, IclR family; Function of strongly homologous gene; factor.
       0.774
sdhB
Succinate dehydrogenase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
  0.766
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
  
 0.764
sdhC
Succinate dehydrogenase/fumarate reductase cytochrome b subunit, b558 family; Function of strongly homologous gene; enzyme.
    
  0.762
CCH87608.1
Fumarylacetoacetate hydrolase family protein; Function of strongly homologous gene; enzyme.
     
 0.754
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.