STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCH87992.15'-nucleotidase (5'-NT); Function of strongly homologous gene; enzyme. (367 aa)    
Predicted Functional Partners:
nudC
NADH pyrophosphatase; Function of strongly homologous gene; enzyme; Belongs to the Nudix hydrolase family.
  
  
  0.892
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.875
add
Adenosine deaminase 3; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
     
  0.864
punA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
     
  0.864
add-2
Adenosine deaminase; Function of strongly homologous gene; enzyme.
     
  0.864
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
     
  0.798
CCH85541.1
Competence/damage-inducible CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
     
  0.785
CCH85747.1
IMP dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.762
CCH89612.1
Endonuclease/exonuclease/phosphatase; Function of strongly homologous gene; enzyme.
     
  0.755
tdk
Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.742
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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