| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCH88022.1 | trmI | MODMU_2593 | MODMU_2597 | Putative haloacid dehalogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.918 |
| CCH88025.1 | CCH88028.1 | MODMU_2596 | MODMU_2599 | RecB family exonuclease; Function of strongly homologous gene; enzyme. | Homologs of previously reported genes of unknown function. | 0.578 |
| CCH88025.1 | arc | MODMU_2596 | MODMU_2598 | RecB family exonuclease; Function of strongly homologous gene; enzyme. | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.571 |
| CCH88025.1 | trmI | MODMU_2596 | MODMU_2597 | RecB family exonuclease; Function of strongly homologous gene; enzyme. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.611 |
| CCH88028.1 | CCH88025.1 | MODMU_2599 | MODMU_2596 | Homologs of previously reported genes of unknown function. | RecB family exonuclease; Function of strongly homologous gene; enzyme. | 0.578 |
| CCH88028.1 | CCH88096.1 | MODMU_2599 | MODMU_2667 | Homologs of previously reported genes of unknown function. | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | 0.518 |
| CCH88028.1 | arc | MODMU_2599 | MODMU_2598 | Homologs of previously reported genes of unknown function. | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.967 |
| CCH88028.1 | trmI | MODMU_2599 | MODMU_2597 | Homologs of previously reported genes of unknown function. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.651 |
| CCH88028.1 | whiB | MODMU_2599 | MODMU_1455 | Homologs of previously reported genes of unknown function. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.419 |
| CCH88028.1 | whiB-3 | MODMU_2599 | MODMU_4581 | Homologs of previously reported genes of unknown function. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.451 |
| CCH88096.1 | CCH88028.1 | MODMU_2667 | MODMU_2599 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | Homologs of previously reported genes of unknown function. | 0.518 |
| CCH88096.1 | trmI | MODMU_2667 | MODMU_2597 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.627 |
| CCH88096.1 | whiB | MODMU_2667 | MODMU_1455 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.808 |
| CCH88096.1 | whiB-3 | MODMU_2667 | MODMU_4581 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.773 |
| CCH89321.1 | trmI | MODMU_3918 | MODMU_2597 | Deoxyribonuclease/rho motif-related TRAM; Function of strongly homologous gene; enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.602 |
| CCH90241.1 | trmI | MODMU_4860 | MODMU_2597 | Homologs of previously reported genes of unknown function. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.602 |
| arc | CCH88025.1 | MODMU_2598 | MODMU_2596 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | RecB family exonuclease; Function of strongly homologous gene; enzyme. | 0.571 |
| arc | CCH88028.1 | MODMU_2598 | MODMU_2599 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Homologs of previously reported genes of unknown function. | 0.967 |
| arc | trmI | MODMU_2598 | MODMU_2597 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.749 |
| rpmD | trmI | MODMU_4901 | MODMU_2597 | 50S ribosomal protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.785 |