| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCH88022.1 | metH | MODMU_2593 | MODMU_2592 | Putative haloacid dehalogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.675 |
| CCH88022.1 | trmI | MODMU_2593 | MODMU_2597 | Putative haloacid dehalogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.919 |
| CCH88025.1 | CCH88028.1 | MODMU_2596 | MODMU_2599 | RecB family exonuclease; Function of strongly homologous gene; enzyme. | Homologs of previously reported genes of unknown function. | 0.603 |
| CCH88025.1 | arc | MODMU_2596 | MODMU_2598 | RecB family exonuclease; Function of strongly homologous gene; enzyme. | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.564 |
| CCH88025.1 | trmI | MODMU_2596 | MODMU_2597 | RecB family exonuclease; Function of strongly homologous gene; enzyme. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.605 |
| CCH88028.1 | CCH88025.1 | MODMU_2599 | MODMU_2596 | Homologs of previously reported genes of unknown function. | RecB family exonuclease; Function of strongly homologous gene; enzyme. | 0.603 |
| CCH88028.1 | CCH88096.1 | MODMU_2599 | MODMU_2667 | Homologs of previously reported genes of unknown function. | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | 0.536 |
| CCH88028.1 | arc | MODMU_2599 | MODMU_2598 | Homologs of previously reported genes of unknown function. | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.966 |
| CCH88028.1 | trmI | MODMU_2599 | MODMU_2597 | Homologs of previously reported genes of unknown function. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.651 |
| CCH88028.1 | whiB | MODMU_2599 | MODMU_1455 | Homologs of previously reported genes of unknown function. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.419 |
| CCH88028.1 | whiB-3 | MODMU_2599 | MODMU_4581 | Homologs of previously reported genes of unknown function. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.451 |
| CCH88096.1 | CCH88028.1 | MODMU_2667 | MODMU_2599 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | Homologs of previously reported genes of unknown function. | 0.536 |
| CCH88096.1 | gltB | MODMU_2667 | MODMU_3403 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.826 |
| CCH88096.1 | trmI | MODMU_2667 | MODMU_2597 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.627 |
| CCH88096.1 | whiB | MODMU_2667 | MODMU_1455 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.776 |
| CCH88096.1 | whiB-3 | MODMU_2667 | MODMU_4581 | Transcriptional regulator, MerR family; Function of strongly homologous gene; regulator. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.773 |
| arc | CCH88025.1 | MODMU_2598 | MODMU_2596 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | RecB family exonuclease; Function of strongly homologous gene; enzyme. | 0.564 |
| arc | CCH88028.1 | MODMU_2598 | MODMU_2599 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Homologs of previously reported genes of unknown function. | 0.966 |
| arc | metH | MODMU_2598 | MODMU_2592 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.500 |
| arc | trmI | MODMU_2598 | MODMU_2597 | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.753 |
