Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CCH88075.1Homologs of previously reported genes of unknown function. (120 aa)    
Predicted Functional Partners:
CCH88074.1
Isochorismatase hydrolase; Function of strongly homologous gene; enzyme.
  
    0.626
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
   
 
 0.603
icmF
Methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.580
CCH89854.1
Protein of unknown function; No homology to any previously reported sequences.
  
  
  0.569
vapC
Cytotoxic translational repressor of toxin-antitoxin stability system, Putative toxin of TAS system; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.538
mutB
Methylmalonyl-CoA mutase large subunit (MCM-alpha); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.493
CCH87887.1
acetyl-CoA carboxylase, biotin carboxylase subunit; Function of strongly homologous gene; enzyme.
  
 
 0.492
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
  0.461
CCH86438.1
L-threonine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
  0.452
CCH86236.1
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Function of strongly homologous gene; enzyme.
  
  
  0.423
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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