STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppsPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)    
Predicted Functional Partners:
CCH88106.1
Conserved protein of unknown function; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.967
eno
Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.920
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
    
 0.916
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
    
 0.864
aceE
Fragment of conserved protein of unknown function (part 1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.822
CCH85681.1
NAD-dependent malic enzyme; Function of strongly homologous gene; enzyme.
  
 
 0.811
CCH87783.1
Phosphoenolpyruvate-utilising enzyme, mobile region; Function of strongly homologous gene; enzyme.
 
    
0.791
tkt
Transketolase; Function of strongly homologous gene; enzyme; Belongs to the transketolase family.
  
 
 0.787
pgi
Glucose-6-phosphate isomerase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
    
 0.786
gcvH
Glycine cleavage system H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
  
 0.780
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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